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Origin BPC-157 originates from a protective protein sequence associated with gastric tissue

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People who have undergone some sort of trauma to the intestines including a gastric bypass or intestinal surgery can be susceptible to vitamin B12 deficiencies since they may have less cells present to produce the protein to which the B12 can attach, resulting in a decreased ability to absorb B12 into the bloodstream

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This is because not all of the cyanocobalamin can be properly converted to the active form, and the leftover must be flushed out of the body